人体内稳态是指人体在生理上调节其内部环境的能力，以保证其稳定性，以应对外界环境和天气的波动。肝脏，肾脏和大脑（下丘脑，自主神经系统和内分泌系统[ 1 ]）有助于维持体内平衡。肝脏是负责代谢的有毒物质，保持碳水化合物代谢。肾脏负责调节血液的水平，将物质重新吸收到血液中，维持血液中的盐和离子水平，调节血液的pH值，以及排泄尿素和其他废物。
一个无法保持平衡，可能会导致死亡或疾病，一种被称为稳态失衡。例如，发生在负反馈机制成为不堪重负的和破坏性的正反馈机制的接管可能心脏衰竭。[ 2 ]其他疾病导致稳态失衡包括糖尿病、脱水、低血糖、高血糖、痛风和血液中的毒素引起的疾病。医疗干预可以帮助恢复体内平衡，并可能防止永久性损害的器官。
Human homeostasis refers to the body’s ability to physiologically regulate its inner environment to ensure its stability in response to fluctuations in the outside environment and the weather. The liver, the kidneys, and the brain (hypothalamus, the autonomic nervous system and the endocrine system) help maintain homeostasis. The liver is responsible for metabolizing toxic substances and maintaining carbohydrate metabolism. The kidneys are responsible for regulating blood water levels, re-absorption of substances into the blood, maintenance of salt and ion levels in the blood, regulation of blood pH, and excretion of urea and other wastes.
An inability to maintain homeostasis may lead to death or a disease, a condition known as homeostatic imbalance. For instance, heart failure may occur when negative feedback mechanisms become overwhelmed and destructive positive feedback mechanisms take over. Other diseases which result from a homeostatic imbalance include diabetes, dehydration, hypoglycemia, hyperglycemia, gout and any disease caused by the presence of a toxin in the bloodstream. Medical intervention can help restore homeostasis and possibly prevent permanent damage to the organs.